Opportunity Information: Apply for CDC RFA GH19 1935
The grant opportunity "Supporting Laboratory Strengthening Activities and Partnerships for Countries Supported under the President's Emergency Plan for AIDS Relief (PEPFAR)" (Funding Opportunity Number CDC RFA GH19 1935) is a CDC-led cooperative agreement designed to strengthen and modernize laboratory systems in countries that receive PEPFAR support. The core purpose is to build durable, in-country capacity so national laboratory networks can operate sustainably over time and reliably support HIV programs and the broader clinical needs of people living with HIV, including the diagnosis and management of tuberculosis (TB) and other opportunistic infections. Rather than functioning as a short-term infusion of resources, the opportunity is framed around long-term systems strengthening, with an emphasis on skills, quality systems, and practical testing capacity that can be maintained locally.
A major pillar of the program is workforce development. The CDC is looking to support enhanced in-service laboratory training and certification programs that strengthen the competencies of laboratory professionals already working in country. This focus signals that the program prioritizes practical, job-embedded training approaches that improve day-to-day performance in real clinical and public health laboratory environments. Certification is specifically mentioned, which implies an interest in structured curricula, competency assessment, and formal recognition of skills that can standardize performance across facilities and help professionalize the laboratory workforce. In practice, this could involve strengthening national training programs, expanding access to mentorship, improving supervisory systems, and supporting continuing professional development pathways that keep staff current as testing technologies and guidelines evolve.
The second pillar is continuous quality improvement through stronger laboratory standards, policies, and systems. This piece is about making quality routine, not episodic. The opportunity highlights strengthening the rules and infrastructure that underpin laboratory reliability: national standards, quality management systems, standard operating procedures, regulatory or accreditation pathways, and the administrative and logistical systems that support consistent operations. A continuous quality improvement approach typically means establishing mechanisms for routine monitoring, corrective actions, and iterative improvement, rather than one-time audits. It also suggests attention to harmonization across the laboratory network so that results are comparable, reliable, and trusted by clinicians and public health decision-makers.
The third pillar is expanding laboratory capacity to perform high-quality testing for Mycobacterium tuberculosis and other opportunistic infections. This recognizes that TB remains a major cause of illness and death among people living with HIV, and that laboratory confirmation and appropriate follow-up testing are essential for timely treatment and for controlling transmission. Increasing capacity here can encompass both technical and operational capabilities: ensuring laboratories can conduct appropriate TB diagnostics at the required level of quality, strengthening specimen referral and transport networks, improving biosafety and biosecurity practices, and ensuring the supporting elements such as equipment maintenance and quality control are functional. By explicitly including other opportunistic infections, the opportunity signals a broader diagnostic strengthening agenda that supports comprehensive HIV care, not only HIV viral monitoring.
A cross-cutting theme throughout the announcement is collaboration and partnership-based capacity building. The program is intended to work through collaborations that enable PEPFAR-supported countries to better diagnose, manage, and treat people living with HIV and HIV-related diseases, including TB. The language emphasizes transfer and sharing of knowledge, tools, technology, and best practices, which suggests CDC expects awardees to serve as technical partners that help countries adopt proven approaches and adapt them to local contexts. This could include developing and disseminating tools for quality management, introducing or optimizing laboratory information systems, supporting technology implementation in ways that fit national strategies, and strengthening coordination between laboratories, clinicians, and public health programs. The cooperative agreement structure also typically indicates substantial involvement by the federal agency, meaning awardees should expect close technical collaboration with CDC during planning, implementation, and monitoring.
Administratively, this is a discretionary health funding opportunity administered by the Department of Health and Human Services, Centers for Disease Control and Prevention (specifically CDC-CGH). It uses a cooperative agreement funding instrument, falls under CFDA 93.067, and was open to unrestricted eligible applicants (with the caveat that any additional eligibility conditions could be clarified in the full notice). The opportunity anticipated up to 4 awards, with an award ceiling listed at $50,000,000. The original posting date was July 6, 2018, and the original closing date was September 4, 2018, with electronic applications due by 11:59 p.m. Eastern Time on the deadline.
Overall, the opportunity is best understood as a large-scale laboratory systems strengthening effort tied directly to PEPFAR country priorities. It aims to leave behind stronger national laboratory networks by improving the laboratory workforce, embedding continuous quality improvement into standards and systems, and ensuring the technical capacity exists to deliver dependable TB and opportunistic infection testing that supports effective HIV care and treatment programs.Apply for CDC RFA GH19 1935
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Supporting Laboratory Strengthening Activities and Partnerships for Countries Supported under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Jul 06, 2018.
- Applicants must submit their applications by Sep 04, 2018 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $50,000,000.00 in funding.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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