Opportunity Information: Apply for CDC RFA JG 26 0058
The Centers for Disease Control and Prevention (CDC), through its Global Health Center (GHC), is soliciting applications for a cooperative agreement titled "Enhancing global laboratory systems to safely manage biological risks, deploy diagnostics, and sequence pathogens to improve capacities for global health threat response and detection" (Funding Opportunity Number: CDC RFA JG 26 0058; CFDA: 93.318). The intent of the opportunity is to protect and improve public health internationally by building stronger, more responsive public health laboratory systems that can detect, characterize, and support response to outbreaks and other health threats, including pathogens with pandemic potential. Because this is a cooperative agreement, applicants should expect substantial CDC involvement during implementation, typically through collaborative planning, technical guidance, and alignment with CDC strategies and performance expectations.
The funded work is organized around several interconnected priorities. First, the NOFO emphasizes strengthening public health laboratory systems, which generally includes improving how laboratory networks are organized, how specimens and data move through the system, and how labs coordinate with surveillance and emergency response partners. Second, it prioritizes improving the public health laboratory workforce, meaning investments in training, competency development, mentoring, and other approaches that ensure laboratories have enough skilled personnel to operate reliably during routine periods and surge during emergencies. Third, it highlights improving biorisk management, which covers safe and secure handling of biological materials, reducing accidental exposures or releases, and strengthening practices that protect laboratory staff and surrounding communities. Fourth, the opportunity calls for reinforcing emergency laboratory preparedness aligned with the 7-1-7 outbreak response paradigm, signaling an emphasis on measurable speed and effectiveness in detection, notification, and response actions, with laboratories positioned as a central enabling function. Fifth, it supports enhancements to laboratory quality management systems, which typically involve standard operating procedures, quality assurance and quality control, proficiency testing, internal audits, corrective actions, and steps toward meeting recognized laboratory standards. Sixth, it aims to enhance diagnostic capacity using two complementary approaches: expanding access to rapid tests suitable for low-resource settings and strengthening genomic sequencing for pathogens that could cause large-scale outbreaks, thereby improving the ability to identify variants, track transmission, and guide public health action.
The NOFO also notes a specific consideration for continuity and expansion of prior investments. Recipients previously funded under CDC-RFA-GH20-2109 may apply under this new opportunity to expand efforts into additional countries, and those countries may receive special consideration. This indicates CDC is seeking to build on existing platforms and partnerships where capacity-building work is already underway, potentially accelerating impact by leveraging established relationships, systems, and trained teams.
In terms of eligibility and administrative details, the opportunity is broadly open to a wide range of applicant types, including state, county, and city governments; special district governments; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations (including small businesses); and effectively unrestricted applicants. The opportunity is categorized as discretionary funding and will be awarded as a cooperative agreement. The original application due date is July 15, 2026. CDC anticipates making approximately three awards. The published award ceiling is listed as 0, which usually means applicants should rely on the full NOFO for the actual funding range, budget expectations, and any constraints or ceilings that may not be captured in the summary field.
Overall, this grant opportunity is geared toward improving the end-to-end ability of countries and laboratory networks to manage biological risks safely, maintain quality operations, and rapidly deploy diagnostics and sequencing during emerging events. The emphasis on workforce, quality systems, and preparedness metrics like 7-1-7 suggests CDC is looking for proposals that combine technical laboratory upgrades with durable systems improvements, measurable performance, and readiness for real-world outbreak demands, especially in settings where resources and infrastructure may be limited.Apply for CDC RFA JG 26 0058
- The Centers for Disease Control-GHC in the health sector is offering a public funding opportunity titled "Enhancing global laboratory systems to safely manage biological risks, deploy diagnostics, and sequence pathogens to improve capacities for global health threat response and detection" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318.
- This funding opportunity was created on 2026-06-12.
- Applicants must submit their applications by 2026-07-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.
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Frequently Asked Questions (FAQs)
What is the official name of this CDC funding opportunity?
The cooperative agreement is titled "Enhancing global laboratory systems to safely manage biological risks, deploy diagnostics, and sequence pathogens to improve capacities for global health threat response and detection."
What is the Funding Opportunity Number (NOFO number) for this program?
The Funding Opportunity Number is CDC RFA JG 26 0058.
What CFDA number is associated with this opportunity?
The CFDA number listed is 93.318.
Which CDC office is running this opportunity?
The opportunity is offered by the Centers for Disease Control and Prevention (CDC) through its Global Health Center (GHC).
What is the overall purpose of this cooperative agreement?
The intent is to protect and improve public health internationally by strengthening public health laboratory systems so they can detect, characterize, and support responses to outbreaks and other health threats, including pathogens with pandemic potential.
Is this a grant or a cooperative agreement?
This funding is a cooperative agreement, which generally means CDC expects substantial involvement during implementation.
What does "substantial CDC involvement" typically mean in this program?
Based on the opportunity description, CDC involvement typically includes collaborative planning, providing technical guidance, and ensuring alignment with CDC strategies and performance expectations during implementation.
How is the funded work organized?
The work is described as being organized around several interconnected priorities, including laboratory system strengthening, workforce improvement, biorisk management, emergency preparedness, quality management systems, and diagnostic and sequencing capacity.
What does "strengthening public health laboratory systems" include?
It generally includes improving how laboratory networks are organized, how specimens and data move through the system, and how laboratories coordinate with surveillance and emergency response partners.
What kinds of activities fall under improving the laboratory workforce?
The NOFO emphasizes investments such as training, competency development, mentoring, and other approaches to ensure laboratories have enough skilled personnel for routine operations and can surge during emergencies.
What is meant by "biorisk management" in this opportunity?
Biorisk management focuses on safe and secure handling of biological materials, reducing accidental exposures or releases, and strengthening practices that protect laboratory staff and surrounding communities.
How does this opportunity address emergency laboratory preparedness?
It calls for reinforcing emergency laboratory preparedness aligned with the 7-1-7 outbreak response paradigm, with laboratories positioned as a central enabling function for detection, notification, and response actions.
What is the 7-1-7 outbreak response paradigm and how is it used here?
The opportunity references 7-1-7 as a preparedness framework emphasizing measurable speed and effectiveness in detection, notification, and response. The NOFO signals that laboratory readiness and performance are expected to support these measurable timelines.
What does strengthening laboratory quality management systems involve?
The NOFO describes quality management systems as typically involving standard operating procedures, quality assurance and quality control, proficiency testing, internal audits, corrective actions, and steps toward meeting recognized laboratory standards.
What does the NOFO mean by enhancing diagnostic capacity?
It highlights two complementary approaches: expanding access to rapid tests suitable for low-resource settings and strengthening genomic sequencing for pathogens that could cause large-scale outbreaks.
Why is genomic sequencing emphasized in this program?
Sequencing is positioned as a way to improve the ability to identify variants, track transmission, and guide public health actions for pathogens with outbreak or pandemic potential.
Does this opportunity build on any prior CDC investments?
Yes. The NOFO notes a specific consideration related to continuity and expansion of prior investments tied to CDC-RFA-GH20-2109.
If an organization was previously funded under CDC-RFA-GH20-2109, can it apply?
Yes. Recipients previously funded under CDC-RFA-GH20-2109 may apply under this new opportunity to expand efforts into additional countries.
Are any countries given special consideration under this NOFO?
The NOFO indicates that additional countries included through expansion by prior CDC-RFA-GH20-2109 recipients may receive special consideration.
Who is eligible to apply for this funding opportunity?
Eligibility is described as broad, including state, county, and city governments; special district governments; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations (including small businesses); and effectively unrestricted applicants.
Is this considered discretionary funding?
Yes. The opportunity is categorized as discretionary funding.
What is the application due date?
The original application due date is July 15, 2026.
How many awards does CDC expect to make?
CDC anticipates making approximately three awards.
Is there a published maximum (ceiling) award amount?
The summary information lists an award ceiling of 0, which commonly means the applicant should rely on the full NOFO for the actual funding range, budget expectations, and any constraints that may not appear in the summary field.
What types of public health threats are the focus of this opportunity?
The focus includes outbreaks and other health threats, including pathogens with pandemic potential, with an emphasis on improved detection, characterization, and response support through laboratory systems.
What is the main theme of the NOFO across all priorities?
The main theme is strengthening end-to-end laboratory and network capability to manage biological risks safely, maintain quality operations, and rapidly deploy diagnostics and sequencing during emerging events, including in settings with limited resources or infrastructure.
What does the NOFO suggest about what CDC is looking for in proposals?
Based on the description, CDC is looking for proposals that combine technical laboratory improvements with durable systems strengthening, measurable performance, and readiness to meet real-world outbreak demands, including alignment with preparedness metrics like 7-1-7.
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