Opportunity Information: Apply for PAR 24 318
The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22 Clinical Trial Required) is a National Institutes of Health funding opportunity designed to help promising postdoctoral researchers make a strong, supported jump into independent faculty roles. It is framed as a transition award: it targets scientists who are currently in postdoctoral fellowships or equivalent early-career research positions and are preparing to move into an assistant professor-level appointment (or a comparable independent research position). The core goal is to help recipients launch an independent biomedical research career, with a particular emphasis on building a sustainable research trajectory in cancer-related fields.
A central feature of this K22 is its purpose as a diversity-focused career development mechanism. The program is administered through the Diversity Training Branch (DTB) within the Center to Reduce Cancer Health Disparities (CRCHD) at NCI, and it specifically invites applications from individuals who are from backgrounds that are nationally underrepresented in biomedical, behavioral, clinical, and/or social sciences. In practical terms, the award is intended to reduce barriers that can make the postdoc-to-faculty transition especially difficult, while also strengthening the diversity of the cancer research workforce and supporting investigators whose perspectives and research interests can contribute to addressing cancer disparities and improving outcomes across populations.
The award provides "protected time" by supporting both salary and research costs for a three-year period, beginning when the awardee starts a tenure-track faculty appointment. The intent is to create enough dedicated time and resources for the new investigator to establish a research program, publish, generate preliminary data, and become competitive for later-stage independent funding. Because this specific announcement is labeled "Clinical Trial Required," applicants should expect that the proposed research and career development plan must include a clinical trial component consistent with NIH definitions and requirements for clinical trials, and should be prepared to address the design, conduct, oversight, and appropriate protections involved in clinical research.
From an eligibility standpoint, the opportunity is listed under NIH as a discretionary grant in the Education and Health activity area (CFDA 93.398). A wide range of applicant organizations can participate, including public and private institutions of higher education, state and local governments, federally recognized tribal governments, tribal organizations, nonprofits (including those with and without 501(c)(3) status), for-profit organizations (other than small businesses), and small businesses, among others. The notice also highlights several institution types often associated with serving underrepresented communities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and eligible federal agencies. At the same time, foreign organizations are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed, reinforcing that the work and the supported appointment are expected to be based within eligible U.S. settings and structures.
Key administrative details from the posting include the funding opportunity number PAR-24-318, with NIH as the issuing agency. The opportunity was created on 2024-12-02, and the listed closing date is 2028-01-07, indicating a multi-year window during which applications may be submitted according to the announcement schedule and NIH receipt dates. The posting does not specify an award ceiling or expected number of awards in the provided text, so applicants typically need to consult the full NIH funding announcement and related NIH policy guidance for the most precise budget limits, allowable costs, and submission instructions tied to this K22 mechanism.Apply for PAR 24 318
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22 Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.398.
- This funding opportunity was created on 2024-12-02.
- Applicants must submit their applications by 2028-01-07.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the NCI CURE K22 (Clinical Trial Required) award?
The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22 Clinical Trial Required) is an NIH/NCI career development funding opportunity intended to support the transition of promising postdoctoral researchers into independent faculty-level research positions. It is structured as a transition award designed to help recipients launch an independent biomedical research career with an emphasis on cancer-related research.
What is the main purpose of this K22?
The core purpose is to help early-career scientists make a strong, supported jump from a postdoctoral or equivalent position into an assistant professor-level appointment (or comparable independent research position), while building a sustainable, independent cancer research trajectory.
Who is this program intended to support?
This award targets scientists currently in postdoctoral fellowships or equivalent early-career research positions who are preparing to move into an independent faculty role, such as a tenure-track assistant professor appointment (or comparable independent research position).
Is this award focused on diversity?
Yes. A central feature of this K22 is that it is a diversity-focused career development mechanism. It specifically invites applications from individuals from backgrounds that are nationally underrepresented in biomedical, behavioral, clinical, and/or social sciences.
Which NCI office administers this opportunity?
The program is administered through the Diversity Training Branch (DTB) within the Center to Reduce Cancer Health Disparities (CRCHD) at the National Cancer Institute (NCI).
How does this award help with the postdoc-to-faculty transition?
It aims to reduce barriers that can make the postdoc-to-faculty transition difficult by providing protected time and resources, including support for salary and research costs, so the awardee can establish an independent program, publish, generate preliminary data, and become competitive for future independent funding.
What does "protected time" mean in this context?
In the context provided, "protected time" refers to supporting the awardee's salary and research costs so they can dedicate substantial time to establishing an independent research program during the early faculty period.
How long is the support period for this award?
The award provides support for a three-year period, beginning when the awardee starts a tenure-track faculty appointment.
When does the K22 funding period begin?
Based on the description provided, the three-year support period begins when the awardee starts a tenure-track faculty appointment (or comparable independent research position).
What does "Clinical Trial Required" mean for applicants?
It means the proposed research and career development plan must include a clinical trial component that aligns with NIH definitions and requirements for clinical trials. Applicants should be prepared to address expectations related to clinical trial design, conduct, oversight, and appropriate protections involved in clinical research.
Does the FAQ content specify what kind of clinical trial must be included?
No. The provided information states that a clinical trial component is required and must be consistent with NIH definitions and requirements, but it does not specify particular trial types, phases, or designs.
What research areas does this K22 emphasize?
The award is oriented toward cancer-related fields, with an emphasis on building an independent cancer research program and strengthening research that can contribute to addressing cancer disparities and improving outcomes across populations.
What is the funding opportunity number?
The funding opportunity number listed is PAR-24-318.
Which agency is issuing this opportunity?
The issuing agency is the National Institutes of Health (NIH), with the opportunity associated with the National Cancer Institute (NCI).
What is the CFDA number and activity area listed?
The opportunity is listed as CFDA 93.398 and is categorized under the Education and Health activity area.
What type of grant mechanism is this listed as?
It is listed under NIH as a discretionary grant.
Which organizations are eligible to apply?
The provided information indicates a wide range of applicant organizations can participate, including public and private institutions of higher education, state and local governments, federally recognized tribal governments, tribal organizations, nonprofits (with or without 501(c)(3) status), for-profit organizations (other than small businesses), and small businesses, among others.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The notice highlights several institution types often associated with serving underrepresented communities, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
Are faith-based or community-based organizations mentioned as eligible?
Yes. Faith-based or community-based organizations are explicitly mentioned among eligible applicant organizations in the provided text.
Are federal agencies eligible to apply?
The provided information mentions eligible federal agencies among the types of institutions that may be eligible.
Are foreign organizations eligible to apply?
No. The provided information states that foreign organizations are not eligible to apply.
Are non-U.S. components of U.S. organizations eligible?
No. The provided information states that non-U.S. components of U.S. organizations are not eligible.
Are foreign components allowed under NIH policy for this opportunity?
No. The description states that foreign components (as defined by NIH policy) are not allowed.
Does the provided information indicate where the supported work and appointment must be based?
Yes. The text reinforces that the work and the supported appointment are expected to be based within eligible U.S. settings and structures.
When was this opportunity created?
The posting indicates the opportunity was created on 2024-12-02.
What is the listed closing date?
The listed closing date is 2028-01-07.
Does the long open window mean applications can be submitted at any time?
The provided information indicates a multi-year window and notes that applications may be submitted according to the announcement schedule and NIH receipt dates. It does not state that submissions are accepted at any time without regard to NIH receipt dates.
Does the provided text specify an award ceiling (maximum budget) for this K22?
No. The provided information explicitly notes that an award ceiling is not specified in the text provided.
Does the provided text specify the expected number of awards?
No. The provided information states that the expected number of awards is not included in the text provided.
Where should applicants look for exact budget limits and allowable costs?
The provided information indicates applicants typically need to consult the full NIH funding announcement and related NIH policy guidance for precise budget limits, allowable costs, and submission instructions tied to this K22 mechanism.
What outcomes is the award designed to support during the three-year period?
As described, the intent is to help the new investigator establish a research program, publish, generate preliminary data, and become competitive for later-stage independent funding.
How does this award relate to cancer health disparities?
The program is administered within NCI's Center to Reduce Cancer Health Disparities and is described as supporting investigators whose perspectives and research interests can contribute to addressing cancer disparities and improving outcomes across populations.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 24 318) also looked into and applied for these:
| Funding Opportunity |
|---|
| NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22 Independent Clinical Trial Not Allowed) Apply for PAR 24 317 Funding Number: PAR 24 317 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08 Clinical Trial Required) Apply for PAR 24 319 Funding Number: PAR 24 319 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08 Clinical Trial Not Allowed) Apply for PAR 24 320 Funding Number: PAR 24 320 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Research to Address Systemic and Structural Barriers and Facilitators to Improve the HIV Pre-Exposure Prophylaxis (PrEP) Care Continuum for People Who Use Substances (R34 Clinical Trials Required) Apply for RFA DA 26 004 Funding Number: RFA DA 26 004 Agency: National Institutes of Health Category: Education, Health Funding Amount: $225,000 |
| Research to Address Systemic and Structural Barriers and Facilitators to Improve the HIV Pre-Exposure Prophylaxis (PrEP) Care Continuum for People Who Use Substances (R01 Clinical Trials Required) Apply for RFA DA 26 003 Funding Number: RFA DA 26 003 Agency: National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional) Apply for PAR 25 299 Funding Number: PAR 25 299 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed) Apply for RFA DA 26 056 Funding Number: RFA DA 26 056 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed) Apply for RFA DA 26 055 Funding Number: RFA DA 26 055 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional) Apply for PAR 25 100 Funding Number: PAR 25 100 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional) Apply for PAR 24 330 Funding Number: PAR 24 330 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Informatics Tools for the Pangenome (U01 Clinical Trial Not Allowed) Apply for RFA HG 25 007 Funding Number: RFA HG 25 007 Agency: National Institutes of Health Category: Education, Health Funding Amount: $400,000 |
| Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional) Apply for PAR 25 321 Funding Number: PAR 25 321 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed) Apply for PAR 25 346 Funding Number: PAR 25 346 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Model Continuums of Care Initiative (MCCI) to Advance Health Equity and End Health Disparities Among Women and Girls in Racial/Ethnic Minority and Other Underserved Communities (U34 Clinical Trials Required) Apply for RFA AA 24 012 Funding Number: RFA AA 24 012 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional) Apply for PAR 25 317 Funding Number: PAR 25 317 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed) Apply for PAR 25 325 Funding Number: PAR 25 325 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| D-START: Data Science Track Award for Research Transition (D/START) (R03-Clinical Trial Optional) Apply for PAS 25 236 Funding Number: PAS 25 236 Agency: National Institutes of Health Category: Education, Health Funding Amount: $100,000 |
| Innovative Biospecimen Science Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed) Apply for RFA CA 25 003 Funding Number: RFA CA 25 003 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed) Apply for RFA CA 25 001 Funding Number: RFA CA 25 001 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed) Apply for RFA CA 25 004 Funding Number: RFA CA 25 004 Agency: National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
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