Opportunity Information: Apply for RFA DA 18 011
Limited Competition Cohort Studies of HIV/AIDS and Substance Abuse (U01) is a National Institutes of Health (NIH) funding opportunity from the National Institute on Drug Abuse (NIDA) designed to keep several established, long-running HIV/AIDS cohort studies among substance-using populations from shutting down and to help them grow in ways that match current public health needs. NIDA has historically invested in multiple longitudinal cohorts that track people over time to understand how HIV risk, infection, prevention, and treatment outcomes unfold in real-world settings where substance use is a major factor. The central idea behind this announcement is that these cohorts are not just individual studies; they function as durable research platforms that can quickly pivot to answer new questions, support partnerships, and provide high-quality data and participant access for future investigator-initiated projects. NIDA notes that the accomplishments of these cohorts have been highly significant, and that four specific cohorts were at risk of being terminated within a year without continued support, which is why the opportunity was released as a limited competition.
The award mechanism is a U01 cooperative agreement, meaning the project is funded as an assistance award but with substantial scientific or programmatic involvement from NIH staff compared with a standard research project grant. In practice, this typically signals a more collaborative relationship with the funding institute, with expectations around coordination, shared priorities, and maintaining a resource that can serve a broader research community. The goal is to support both maintenance and expansion: keeping the cohort infrastructure intact, continuing participant follow-up, and strengthening the ability to address emerging or high-priority research questions that sit at the intersection of HIV/AIDS and substance abuse. Emphasis is placed on multidisciplinary research, reflecting the reality that HIV outcomes in substance-using populations are shaped by behavioral health, clinical care, prevention access, social and structural factors, and changing drug use patterns.
A major focus of the continued support is on recruitment and retention of participants, which is critical to preserving the scientific value of longitudinal cohorts. By continuing to enroll and follow participants, the cohorts can provide insight into how the demographics of the HIV epidemic are shifting among high-risk substance-using populations in the United States, including changes in risk behaviors, access to prevention tools, treatment engagement, and health outcomes over time. NIDA also highlights that maintaining these cohorts helps preserve an efficient, ready-to-use platform for collaboration with other investigators, allowing the research community to respond faster to new HIV prevention and treatment questions as they arise in the context of substance use.
This is a discretionary funding opportunity (RFA-DA-18-011) within the NIH assistance framework, associated with CFDA number 93.279, and it anticipated making about four awards. The opportunity was created on June 14, 2017, with an original closing date of September 29, 2017. While the source summary does not list a specific award ceiling amount, the overall intent is clearly centered on sustaining existing NIDA-supported cohorts and extending their capacity, rather than starting entirely new cohorts from scratch.
Eligibility is restricted, consistent with the "limited competition" label. The summary indicates eligible applicants include private institutions of higher education, and it explicitly excludes non-U.S. entities and foreign involvement: non-domestic (non-U.S.) institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. The practical implication is that funded work must be led and conducted within allowable U.S.-based institutional structures, with the cohort efforts focused on the U.S. epidemic among high-risk substance-using populations. For full details on who can apply and the exact scope of the limited competition, applicants would need to rely on the full FOA text.Apply for RFA DA 18 011
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Limited Competition Cohort Studies of HIV/AIDS and Substance Abuse (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279.
- This funding opportunity was created on 2017-06-14.
- Applicants must submit their applications by 2017-09-29. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Private institutions of higher education.
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| Collaborative Research Network for Fusion Oncoproteins in Childhood Cancers (U54) Apply for RFA CA 17 049 Funding Number: RFA CA 17 049 Agency: National Institutes of Health Category: Education, Health Funding Amount: $2,500,000 |
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