Opportunity Information: Apply for HRSA 21 110
The Evaluating Genetic and Genomic Medicine Implementation and Outcomes in the Regional Genetics Networks (EGGMIO-RGN) opportunity is a supplemental funding announcement from the Health Resources and Services Administration (HRSA) within the U.S. Department of Health and Human Services. It sits under the existing Regional Genetics Networks (RGN) program (original program reference HRSA-20-046) and is designed to help current RGN awardees take a closer, more rigorous look at how well their ongoing genetics and genomics activities are working in real-world practice. The central idea is not to launch brand-new services, but to evaluate strategies and activities that the networks are already using to expand access to genetic and genomic services, particularly for individuals and families who are underserved or face barriers to care.
At its core, EGGMIO-RGN is about evaluation: measuring implementation and outcomes to understand what is effective, for whom, and under what conditions. HRSA is looking for focused, well-designed assessments that can generate practical findings, such as what improves uptake of genomic tools in clinical settings, what service delivery models produce better access or health outcomes, and what program approaches can be replicated by others. The expectation is that recipients will study the utility, applicability, and effectiveness of one or more existing RGN program activities, producing results that can guide their own improvements while also contributing lessons to the broader field of genetic and genomic medicine and public health.
HRSA plans to make up to three awards through a cooperative agreement mechanism, meaning the agency typically has substantial involvement in the funded work compared with a standard grant. The opportunity is categorized as discretionary funding within the health activity area (CFDA 93.110). Eligibility is listed broadly as "Others (see text field entitled Additional Information on Eligibility for clarification)," but the announcement makes clear that this is supplemental funding under the RGN program, so the practical target audience is RGN recipients that already hold awards under HRSA-20-046. The funding opportunity number is HRSA 21 110. The notice was created April 22, 2021, with an original closing date of June 7, 2021, and HRSA anticipated three total awards. The award ceiling is listed as 0 in the provided record, which often indicates that the cap may be defined elsewhere in the full notice or handled on a supplemental, case-specific basis.
In terms of what HRSA wants evaluated, the announcement highlights several example topics. One is outreach and engagement strategies aimed at primary care providers and other non-genetics clinicians, including education, training, or clinical resources that help them use genomics appropriately in patient care. Another is perceived clinical utility, meaning whether providers, patients, and families believe that RGN-developed genomic resources or tools are helpful across the full care journey, from diagnosis through treatment planning and long-term management. The opportunity also points to evaluation of nontraditional service modalities, such as telehealth-enabled genetic or genomic services, with attention both to implementation (how the service is delivered, adopted, and sustained) and outcomes (such as access, timeliness, quality, or clinical impact). HRSA is also interested in whether RGN-created resources or strategies can be transferred across regions, including adaptations through multi-RGN collaboration and dissemination of lessons learned to address common unmet needs. Finally, the notice calls out the impact of integrating the latest scientific evidence related to particular genetic or genomic conditions, focusing on whether evidence updates improve the usefulness and effectiveness of the program activity.
Overall, EGGMIO-RGN is best understood as an applied evaluation initiative meant to turn experience from the Regional Genetics Networks into actionable evidence. By funding a small number of rigorous evaluations of established RGN strategies, HRSA aims to identify best practices for implementing genetic and genomic advances in clinical and public health settings, while keeping equity and access for underserved populations at the center of the work.Apply for HRSA 21 110
- The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Evaluating Genetic and Genomic Medicine Implementation and Outcomes in the Regional Genetics Networks (EGGMIO-RGN)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.110.
- This funding opportunity was created on Apr 22, 2021.
- Applicants must submit their applications by Jun 07, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
What is the EGGMIO-RGN funding opportunity?
Evaluating Genetic and Genomic Medicine Implementation and Outcomes in the Regional Genetics Networks (EGGMIO-RGN) is a supplemental funding announcement from the Health Resources and Services Administration (HRSA), part of the U.S. Department of Health and Human Services. It supports evaluation work within the existing Regional Genetics Networks (RGN) program.
Who is HRSA, and what is their role in this opportunity?
HRSA (Health Resources and Services Administration) is the federal agency offering and administering this opportunity. HRSA is also expected to be substantially involved in the funded work because the awards are made as cooperative agreements.
How does EGGMIO-RGN relate to the Regional Genetics Networks (RGN) program?
EGGMIO-RGN sits under the existing RGN program and is described as supplemental funding connected to the original RGN program reference HRSA-20-046. The focus is on evaluating RGN activities that are already underway rather than launching entirely new services.
What is the main purpose of EGGMIO-RGN?
The central purpose is rigorous evaluation: measuring implementation and outcomes of current RGN genetics and genomics strategies in real-world practice. HRSA is looking for focused assessments that clarify what works, for whom, and under what conditions, especially in efforts that expand access for underserved individuals and families or people facing barriers to care.
Is this opportunity meant to fund new genetics or genomics services?
No. The stated emphasis is not to launch brand-new services. Instead, EGGMIO-RGN is meant to evaluate strategies and activities the networks are already using to expand access to genetic and genomic services.
What kinds of questions should the evaluation try to answer?
HRSA is seeking evaluations that generate practical findings, such as which approaches improve uptake of genomic tools in clinical settings, what service delivery models improve access or outcomes, and which program strategies are replicable by others.
What types of activities or strategies does HRSA want evaluated?
The announcement provides example topics, including: outreach and engagement strategies aimed at primary care and other non-genetics clinicians; perceived clinical utility of RGN-developed tools and resources; nontraditional service modalities such as telehealth-enabled genetic or genomic services; transferability of RGN-created strategies across regions; and the impact of integrating updated scientific evidence related to specific genetic or genomic conditions.
What does HRSA mean by evaluating "implementation" and "outcomes"?
Based on the description, implementation evaluation focuses on how an activity or service is delivered, adopted, and sustained in practice. Outcomes evaluation focuses on the results of those activities, such as access, timeliness, quality, or clinical impact.
What is "perceived clinical utility" in this opportunity?
Perceived clinical utility refers to whether providers, patients, and families believe that RGN-developed genomic resources or tools are helpful across the care journey, including diagnosis, treatment planning, and long-term management.
Does HRSA specifically mention telehealth in this opportunity?
Yes. The opportunity highlights evaluation of nontraditional service modalities, including telehealth-enabled genetic or genomic services, with attention to both implementation and outcomes.
What does HRSA mean by transferability across regions?
HRSA is interested in whether resources or strategies created in one RGN can be transferred or adapted for use in other regions, including through multi-RGN collaboration and dissemination of lessons learned to address common unmet needs.
How many awards does HRSA plan to make?
HRSA anticipated up to three total awards under this supplemental announcement.
What funding mechanism is being used?
The opportunity is offered as a cooperative agreement, which typically means HRSA has substantial involvement in the funded work compared with a standard grant.
What is the funding opportunity number?
The funding opportunity number is HRSA 21 110.
What is the CFDA number and activity area associated with this opportunity?
The opportunity is listed under CFDA 93.110 and is categorized in the health activity area as discretionary funding.
Who is eligible to apply?
Eligibility is listed broadly as "Others (see text field entitled Additional Information on Eligibility for clarification)," but the description indicates this is supplemental funding under the RGN program. Practically, it is aimed at current RGN recipients holding awards under HRSA-20-046.
What is the application timeline mentioned in the provided information?
The notice was created on April 22, 2021, and the original closing date was June 7, 2021.
What is the award ceiling for EGGMIO-RGN?
In the provided record, the award ceiling is listed as 0. This often indicates that the cap may be defined elsewhere in the full notice or handled on a supplemental, case-specific basis.
What kind of deliverable or end result is HRSA looking for?
HRSA is looking for well-designed evaluations that produce actionable evidence about the utility, applicability, and effectiveness of existing RGN program activities. The results should support improvements within the networks and contribute lessons to the broader field of genetic and genomic medicine and public health.
How does the opportunity address equity and access?
The opportunity emphasizes expanding access to genetic and genomic services and explicitly highlights individuals and families who are underserved or face barriers to care as a central focus for evaluation.
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