Incorporating Patient-Reported Outcomes into Clinical Care for Type 1 Diabetes (R01 Clinical Trial Required) | RFA DK 17 027

Opportunity Information: Apply for RFA DK 17 027

The National Institutes of Health (NIH) announced a discretionary grant opportunity, RFA-DK-17-027, titled "Incorporating Patient-Reported Outcomes into Clinical Care for Type 1 Diabetes (R01 Clinical Trial Required)." The main purpose of this funding announcement is to support research that tests real-world, healthcare-setting approaches for using patient-reported outcomes (PROs) as practical tools in clinical care for people with type 1 diabetes. The emphasis is on integrating PRO information into routine care in ways that strengthen patient-centered treatment, improve communication and decision-making between patients and clinicians, and ultimately lead to better health and quality-of-life outcomes. Because this is an R01 with a clinical trial required, applicants are expected to propose and carry out a study that prospectively evaluates an intervention or implementation approach, rather than only observational or descriptive work.

At its core, the opportunity is about moving PROs beyond research surveys and into everyday diabetes care workflows. PROs typically capture information that only the patient can directly report, such as diabetes distress, hypoglycemia fear, treatment burden, sleep, pain, mood, or perceived functioning. The FOA’s intent is to fund studies that test how collecting these measures, feeding them back to care teams, and acting on them can improve patient-centered care for type 1 diabetes. In practice, this could include testing clinic-based systems for routine PRO screening, evaluating how PRO results trigger tailored education or behavioral support, studying ways to embed PRO summaries in electronic health records for use during visits, or comparing different strategies for responding to PRO signals (for example, stepped-care pathways, referral protocols, or shared decision-making tools). The focus is explicitly on approaches that can be deployed within healthcare settings, not just on developing new questionnaires.

The funding instrument is an NIH research project grant (R01). The opportunity is categorized under Food and Nutrition and Health, and is associated with CFDA number 93.847. The posted award ceiling is $375,000, indicating the upper bound of the funding amount reflected in the opportunity summary. The original closing date listed for applications was July 10, 2018, and the opportunity record shows a creation date of February 14, 2018. The listing also notes "ExpectedAwards:" but does not provide a number in the source text provided, so the anticipated number of awards is not specified here.

Eligibility is broad across many U.S.-based organization types. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with 501(c)(3) status (and nonprofits without 501(c)(3) status), excluding institutions of higher education; for-profit organizations other than small businesses; and small businesses. The announcement also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal government agencies, Indian/Native American tribal governments other than federally recognized, and U.S. territories or possessions.

Foreign involvement is restricted. While the text mentions "Non-domestic (non-U.S.) Entities (Foreign Organizations)" in a list of other eligible applicants, it then clearly states that non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, that non-domestic components of U.S. organizations are not eligible to apply, and that foreign components (as defined in the NIH Grants Policy Statement) are not allowed. In other words, the work must be led and conducted within eligible U.S.-based applicant structures, without foreign components.

Overall, this FOA is geared toward practical, testable clinical trial projects that demonstrate whether and how integrating patient-reported outcomes into routine type 1 diabetes care improves outcomes that matter to patients and clinicians. Competitive projects under this type of announcement typically align PRO collection with actionable care pathways, demonstrate feasibility within real clinical workflows, and evaluate impacts on both patient-centered outcomes (like distress, functioning, satisfaction, or treatment burden) and diabetes-related clinical outcomes where appropriate.

• The National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Incorporating Patient-Reported Outcomes into Clinical Care for Type 1 Diabetes (R01 Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
• This funding opportunity was created on 2018-02-14.
• Applicants must submit their applications by 2018-07-10. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $375,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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